Pls I need your help it’s important

I need your advice on something. One of my best friends lost her mom and her dad (when she was born) and now she lives with her grandma. But her grandma isn't her mom, so she never talks to her about her problems or what’s going on in her life. Instead, she talks to me or our other best friends.

Two days ago, our other best friends—who are also close with her—were really annoyed while talking about her. They were saying things like, "We're not her moms, but she doesn't have one, so what are we supposed to do?" When I asked them what happened, they just said, "Ask her yourself."

Yesterday, I ran into her and asked her about it. She told me she had smoked (I won't say how old she is, but she is definitely too young to smoke, (we are freshman high school)). I asked her if someone had forced her at first because she’s way too nice, and I thought maybe it was people from her class. (By the way, we don't hang out as much anymore because she’s doing a shorter school program, so we're separated, but we still see her in the schoolyard). She told me that a girl had lent her a vape and she smoked it. Then, she shocked me by saying, "Actually, I bought myself a vape." I didn’t even know what to say, and right at that moment, I randomly had to leave. Before I left, she told me, "Please don't tell the other girls."

Later that evening, when I was going out, I ran into her again. I was with one of our best friends at the time, so I couldn't bring it up, because our friend only knows about the first time she smoked, not that she actually bought her own vape. While we were walking, she quickly whispered in my ear, "Oh yeah, I also drank alcohol."

Like, whaaaat? She is way too young for this. I'm so worried about her because she’s clearly getting influenced by the people in her class, her "friends." I really need your advice because I honestly have no idea what to do…